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Verification register Bio, Health & Neuro

Readiness verdict

eGenesis Genetically-Edited Pig Kidney Xenotransplant (Richard Slayman, Mass General)

A dated reading of what is claimed, reported, and independently verified in the current evidence.

As of
2026-07-27
Revision
1
Method
v1.3.0

Current reading

Readiness band and full integer triple

AI-assisted assembly · derived results

Readiness band

Emerging

Primary summary from verified readiness

Confidence
66% · stale
Computed at
2026-07-27T18:59:01.472053+00:00
Claimed
45

Public ambition and stated capability

Reported
38

Observed practitioner reporting

Verified
28

Independently supported evidence

Gap
+17

Claimed leads verified

Evidence strength Growing

Decision

What the current evidence supports

Human editorial judgment · 2026-07-27

Track; not yet

Why
The Slayman case proved surgical/immunological feasibility of a 69-edit CRISPR pig kidney in a living human and opened the modern xenotransplant era, but rejection remains unresolved (Looney's kidney failed at 4mo9d) and the patient count is still single digits under expanded-access/early trial protocols -- genuinely promising, not yet a repeatable clinical modality.
Next
Re-check when eGenesis's FDA-cleared (2025-09-08) Phase 1/2/3 EGEN-2784 trial reports interim safety/efficacy data on additional enrolled patients, or when a recipient surpasses 12 months rejection-free -- whichever comes first.

Constraints

Blockers

No named blocker is present in the current public projection.

Evidence summary

Derived counts

AI-assisted assembly

Total
6
Tier 1
0
Tier 2
5
Tier 3
1
Supports
3
Contradicts
2
Context
1
Latest observed
2025-09-08

Counts and dates only. Raw signals, private excerpts, trust records, and internal corpus material are not published here.

Publication record

Revisions

Initial public reading

  1. 2026-07-27 Reading moved from emerging to emerging.

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