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Verification register Bio, Health & Neuro

Readiness verdict

Boltz-2

A dated reading of what is claimed, reported, and independently verified in the current evidence.

As of
2026-08-20
Revision
1
Method
v1.3.0

Current reading

Readiness band and full integer triple

AI-assisted assembly · derived results

Readiness band

Ready

Primary summary from verified readiness

Confidence
68% · stale
Computed at
2026-08-20T10:52:07.705102+00:00
Claimed
75

Public ambition and stated capability

Reported
66

Observed practitioner reporting

Verified
57

Independently supported evidence

Gap
+18

Claimed leads verified

Evidence strength Strong

Decision

What the current evidence supports

Human editorial judgment · 2026-08-20

Adopt with guardrails

Why
Open MIT-licensed, fast, and strong on held-out FEP+/CASP16, but a large body of independent benchmarks documents narrow dynamic range, memorization, and instability — usable for triage, not as a physics replacement.
Next
Deploy for fast triage/enrichment in early virtual screening with target-specific calibration and a physics-based (FEP) confirmation gate; avoid molecular glues and flexible-pocket targets, and validate against in-house actives before trusting rankings.

Constraints

Blockers

No named blocker is present in the current public projection.

Evidence summary

Derived counts

AI-assisted assembly

Total
14
Tier 1
0
Tier 2
8
Tier 3
6
Supports
6
Contradicts
6
Context
2
Latest observed
2026-02-01

Counts and dates only. Raw signals, private excerpts, trust records, and internal corpus material are not published here.

Publication record

Revisions

Initial public reading

  1. 2026-07-19 Reading moved from ready to ready.

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