Verification register Bio, Health & Neuro
Current reading
Readiness band and full integer triple
AI-assisted assembly · derived results
Readiness band
Watch
Primary summary from verified readiness
- Confidence
- 47% · stale
- Computed at
- 2026-07-23T19:13:14.723463+00:00
- Claimed
- 60
- Reported
- 47
- Verified
- 38
- Gap
- +22
Public ambition and stated capability
Observed practitioner reporting
Independently supported evidence
Claimed leads verified
Evidence strength Growing
Decision
What the current evidence supports
Human editorial judgment · 2026-07-23
Track; not yet
- Why
- AlphaProteo is closed and partner-gated with target-dependent success (a hard target, TNFa, failed outright) and no resolved path through PK/immunogenicity/manufacturing; a peer-reviewed open alternative (BindCraft, Nature 2025) already delivers comparable one-shot binder design with public code and weights, so there is no current integration opportunity for our stack -- but the sub-category AlphaProteo founded remains load-bearing for how OpenFold3/RFdiffusion3 are now measured.
- Next
- Re-evaluate if DeepMind or Isomorphic Labs open any AlphaProteo tooling, publish a head-to-head benchmark against BindCraft/RFdiffusion3, or attribute a specific clinical candidate to AlphaProteo-designed binders; until then keep tracking the field via the open successors already in the register (RFdiffusion3, OpenFold3).
Constraints
Blockers
No named blocker is present in the current public projection.
Evidence summary
Derived counts
AI-assisted assembly
- Total
- 5
- Tier 1
- 0
- Tier 2
- 1
- Tier 3
- 4
- Supports
- 2
- Contradicts
- 3
- Context
- 0
- Latest observed
- 2026-04-27
Counts and dates only. Raw signals, private excerpts, trust records, and internal corpus material are not published here.
Publication record
Revisions
Initial public reading
- 2026-07-23 Reading moved from watch to watch.