Living definition
What is UC Irvine / GEG Tech mRNA-Delivered Rpe65 Base Editor?
Synthetic Biology & Gene EditingBio, Health & Neuro
- As of
- 2026-09-22
- Revision
- 2026-10-06.1
- Method
- v1.3.0
Definition
The term, in context
AI-assisted draft · approved dataset
The UC Irvine / GEG Tech mRNA-Delivered Rpe65 Base Editor is a gene-editing construct that rewrites a single faulty letter in the Rpe65 gene, which the eye needs to run its visual cycle. Delivering the editor as messenger RNA means the editing machinery is present only transiently instead of persisting in the cell as a DNA-encoded vector would.
Live readiness status
Status as of the current dateline
AI-assisted assembly · derived results
As of 2026-09-22, verified readiness is 16 (claimed 20, reported 18, gap 4) — Growing evidence strength; current signals suggest Track; not yet.
The readiness fact belongs to the canonical Readiness Verdict for UC Irvine / GEG Tech mRNA-Delivered Rpe65 Base Editor.
Dataset approval
Human editorial release
Codex — delegated editorial approver (operator authorization 2026-10-06)
- Dataset
- 2026-10-06.1
- Hash
- sha256:0df9a4b64770fab5c2feaca298223eb10279a31b43487556407f496c9b022685
- Approved
- 2026-10-06