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Verification register Bio, Health & Neuro

Living definition

What is PM577a (in vivo Prime Editor for Wilson Disease)?

Synthetic Biology & Gene Editing Bio, Health & Neuro

As of
2026-07-19
Revision
2026-07-19.2
Method
v1.3.0

Definition

The term, in context

AI-assisted draft · approved dataset

PM577a is an experimental gene-editing therapy that uses prime editing, delivered directly into the body, to correct the specific mutation that causes Wilson disease.

Live readiness status

Status as of the current dateline

AI-assisted assembly · derived results

As of 2026-07-19, verified readiness is 31 (claimed 40, reported 35, gap 9) — Strong evidence strength; current signals suggest Too early to adopt.

The readiness fact belongs to the canonical Readiness Verdict for PM577a (in vivo Prime Editor for Wilson Disease).

Dataset approval

Human editorial release

pragma.vision editorial — standing authorization (operator dev@soft.house, 2026-07-17)

Dataset
2026-07-19.2
Hash
sha256:5b6f2a037b720dbb2ee4216d94ab16dcb623c06c65387010d64145dfda66d13d
Approved
2026-07-19

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